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For two years, “Mike” bought counterfeit Viagra from Hitsman and sent samples to Amy Callanan, a senior scientist at Pfizer. Callanan, who works at Pfizer’s R&D campus in Groton, Connecticut, is now sitting with me at a large conference table scattered with baggies, blister packs, and bottles of pills. Callanan spends most of her time analyzing fake pharmaceuticals, looking for chemical clues that may lead investigators to culprits. She picks up two small cardboard boxes. One box contains legitimate Viagra, the other is full of fakes. To me, they look almost identical: same size, same wide blue stripes down the left-hand side, legitimate-looking Pfizer logos and holograms.Study 3: This study was designed to evaluate the effect of single doses of 5 mg vardenafil (stage 1) and 10 mg vardenafil (stage 2) compared to placebo, when administered to a single cohort of BPH patients (n=24) on stable therapy with alfuzosin 10 mg daily for at least four weeks. The design was a randomized, double blind, 3-period cross-over study. Vardenafil or placebo was administered 4 hours after the administration of alfuzosin. Blood pressure and pulse were evaluated over a 10-hour interval after dosing of vardenafil or placebo. For BP results see Table 4.
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